National Quality Forum #: None
Description: Percentage of identified inappropriate antiretroviral (ARV) regimen components prescriptions that are resolved by the ADAP during the measurement year
Numerator: Number of ARV regimen components prescriptions from the denominator that are resolved by the ADAP during the measurement year
Denominator: Number of inappropriate ARV regimen components prescriptions included in the Department of Health and Human Services (HHS) Clinical Practice Guidelines, "What Not to Use"1 and "What Not to Start: Regimens Not Recommended for Use in Antiretroviral-Naive Children"2 that are identified by ADAP
Exclusions: For clients who receive ADAP services with multiple sources of funding for their medications, the ADAP is responsible for identifying only ARV regimen components funded by ADAP
Data Elements: Was the prescribed ARV regimen components included in the HHS Clinical Practice Guidelines, "Antiretroviral Regimens or Components That Should Not Be Offered At Any Time"1 and "Antiretroviral Regimens or Components That Should Not Be Offered for Treatment of Human Immunodeficiency Virus (HIV) Infection in Children"2 identified by the ADAP during the measurement year? (Y/N)
- If yes, specify the components, the prescribing clinician and client.
- In response to the ADAP contacting the prescribing clinician, was the ARV regimen components prescription subsequently modified by the prescribing clinician to an ARV regimen components that is not included the HHS Clinical Practice Guidelines, "Antiretroviral Regimens or Components That Should Not Be Offered At Any Time"1 and "Antiretroviral Regimens or Components That Should Not Be Offered for Treatment of Human Immunodeficiency Virus (HIV) Infection in Children"2 or was the ARV regimen components clinically justified by the prescribing clinician? (Y/N)
Data Sources: Recipient's ADAP data system
National goals, targets, or benchmarks for comparison
The HIV Quality Measures (HIVQM) Module is a tool within the RSR portal that allows recipients to enter aggregate data specific to the HRSA HAB Performance Measures. The HIVQM Module allows recipients to conduct point-in-time benchmarking across Ryan White HIV/AIDS Programs that use the module.
Department of Health and Human Services Clinical Practice Guidelines
Some antiretroviral regimens or components are not generally recommended because of suboptimal antiviral potency, unacceptable toxicities or pharmacologic concerns. Refer to the Department of Health and Human Services Clinical Practice Guidelines for additional information.1-2
References/notes
1 Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents with HIV (PDF - 4 MB). Department of Health and Human Services. Available online. Accessed August H-1 through H-3.
2 Panel on Antiretroviral Therapy and Medical Management of HIV-Infected Children. Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection (PDF - 5 MB). Department of Health and Human Services. Available online. Accessed August 2023. F-38 through F-44.